Estimate the extent of etiologic heterogeneity |
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Estimate the incremental explained risk variation in a case-control study |
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Estimate the incremental explained risk variation in a case-only study |
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Test for etiologic heterogeneity |
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Test for etiologic heterogeneity of risk factors according to disease subtypes in a case-control study |
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Test for etiologic heterogeneity of risk factors according to individual disease markers in a case-control study |
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Identify optimal D solution |
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Obtain optimal D solution based on k-means clustering of disease marker data in a case-control study |
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Obtain overall p-value for factor variable |
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Post-hoc test to obtain overall p-value for a factor variable used in a
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Example DatasetsSimulated data to illustrate package use |
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Simulated subtype data |